Publications
The BETTER-B project builds on a large body of breathlessness research previously undertaken by the international consortium of partners from the UK, Italy, Ireland, Poland, Germany, Switzerland and Australia. The publications are ordered by release date.
Ferreira DH, Ekström M, Bajwah S, Fazekas B, Currow DC.
Regular, low-dose, sustained-release morphine for persisting breathlessness in interstitial lung disease - a randomised, double-blind, placebo-controlled, crossover trial.
Eur Respir J. 2023 Sep 7:2300702. doi: 10.1183/13993003.00702-2023. Epub ahead of print. PMID: 37678949.
West A, Chaudhuri N, Barczyk A, Wilsher ML, Hopkins P, Glaspole I, Corte TJ, Šterclová M, Veale A, Jassem E, Wijsenbeek MS, Grainge C, Piotrowski W, Raghu G, Shaffer ML, Nair D, Freeman L, Otto K, Montgomery AB. Inhaled pirfenidone solution (AP01) for IPF: a randomised, open-label, dose-response trial.
Thorax. 2023 Sep;78(9):882-889. doi: 10.1136/thorax-2022-219391. Epub 2023 Mar 22. PMID: 36948586.
Date K, Williams B, Cohen J, Chaudhuri N, Bajwah S, Pearson M, Higginson I, Norrie J, Keerie C, Tuck S, Hall P, Currow D, Fallon M, Johnson M.
Modified-release morphine or placebo for chronic breathlessness: the MABEL trial protocol.
ERJ Open Res. 2023 Aug 14;9(4):00167-2023. doi: 10.1183/23120541.00167-2023. PMID: 37583966; PMCID: PMC10423982.
Nkhoma KB, Farrant L, Mzimkulu O, Hunter J, Higginson I, Gao W, Maddocks M, Gwyther L, Harding R.
High Prevalence and Burden of Physical and Psychological Symptoms in a Chronic Obstructive Pulmonary Disease Population in Primary Care Settings in South Africa.
Int J Chron Obstruct Pulmon Dis. 2023 Aug 2;18:1665-1679. doi: 10.2147/COPD.S395834. PMID: 37554921; PMCID: PMC10404593.
Janssen DJA, Bajwah S, Boon MH, Coleman C, Currow DC, Devillers A, Vandendungen C, Ekström M, Flewett R, Greenley S, Guldin MB, Jácome C, Johnson MJ, Kurita GP, Maddocks M, Marques A, Pinnock H, Simon ST, Tonia T, Marsaa K.
European Respiratory Society clinical practice guideline: palliative care for people with COPD or interstitial lung disease.
Eur Respir J. 2023 Aug 17;62(2):2202014. doi: 10.1183/13993003.02014-2022. PMID: 37290789.
Osadnik CR, Brighton LJ, Burtin C, Cesari M, Lahousse L, Man WDC, Marengoni A, Sajnic A, Singer JP, Ter Beek L, Tsiligianni I, Varga JT, Pavanello S, Maddocks M.
European Respiratory Society statement on frailty in adults with chronic lung disease.
Eur Respir J. 2023 Aug 17;62(2):2300442. doi: 10.1183/13993003.00442-2023. PMID: 37414420.
Schloesser K, Bergmann A, Eisenmann Y, Pauli B, Pralong A, Hellmich M, Oberste M, Hamacher S, Tuchscherer A, Frank KF, Randerath W, Herkenrath S, Leupoldt AV, Niecke A, Simon ST.
Interaction of panic and episodic breathlessness among patients with life-limiting diseases: a cross-sectional study.
Ann Palliat Med. 2023 Aug 25:apm-22-1304. doi: 10.21037/apm-22-1304. Epub ahead of print. PMID: 37691331.
Disler R, Henwood B, Luckett T, Pascoe A, Donesky D, Irving L, Currow DC, Smallwood N.
Knowledge and Attitudes of Allied Health Professionals Towards End-Of-Life and Advance Care Planning Discussions With People With COPD: A Cross-Sectional Survey Study.
Am J Hosp Palliat Care. 2023 Aug;40(8):856-871. doi: 10.1177/10499091221134777. Epub 2022 Oct 20. PMID: 36266239.
Lovell N, Etkind SN, Davies JM, Prentice W, Higginson IJ, Sleeman KE.
Effect of listening to breathing recordings on self-reported breathlessness: a public experiment.
Eur Respir J. 2023 Jul 20;62(1):2201439. doi: 10.1183/13993003.01439-2022. PMID: 37105574; PMCID: PMC10356964.
Melzer T, Kahnert K.
Schrittzähler zum Anspornen nach COPD-Exazerbation.
MMW Fortschr Med. 2023 Jul;165(13):24-26. German. doi: 10.1007/s15006-023-2816-0. PMID: 37420058.
McAuley HJC, Maddocks M.
Gaining muscle mass in COPD: a work in progress.
ERJ Open Res. 2023 Jul 31;9(4):00336-2023. doi: 10.1183/23120541.00336-2023. PMID: 37529635; PMCID: PMC10388174.
Nolan CM, Brighton LJ, Mo Y, Bayly J, Higginson IJ, Man WD, Maddocks M.
Meditative movement for breathlessness in advanced COPD or cancer: a systematic review and meta-analysis.
Eur Respir Rev. 2023 Jun 21;32(168):220243. doi: 10.1183/16000617.0243-2022. PMID: 37343961; PMCID: PMC10282812.
Maddocks M, Brighton LJ, Alison JA, Ter Beek L, Bhatt SP, Brummel NE, Burtin C, Cesari M, Evans RA, Ferrante LE, Flores-Flores O, Franssen FME, Garvey C, Harrison SL, Iyer AS, Lahouse L, Lareau S, Lee AL, Man WD, Marengoni A, McAuley HJC, Rozenberg D, Singer JP, Spruit MA, Osadnik CR.
Rehabilitation for People with Respiratory Disease and Frailty: An Official American Thoracic Society Workshop Report.
Ann Am Thorac Soc. 2023 Jun;20(6):767-780. doi: 10.1513/AnnalsATS.202302-129ST. PMID: 37261787; PMCID: PMC10257033.
Kahnert K, Jörres RA, Behr J, Welte T.
The Diagnosis and Treatment of COPD and Its Comorbidities.
Dtsch Arztebl Int. 2023 Jun 23;120(25):434-444. doi: 10.3238/arztebl.m2023.027. PMID: 36794439; PMCID: PMC10478768.
Maher TM, Ford P, Brown KK, Costabel U, Cottin V, Danoff SK, Groenveld I, Helmer E, Jenkins RG, Milner J, Molenberghs G, Penninckx B, Randall MJ, Van Den Blink B, Fieuw A, Vandenrijn C, Rocak S, Seghers I, Shao L, Taneja A, Jentsch G, Watkins TR, Wuyts WA, Kreuter M, Verbruggen N, Prasad N, Wijsenbeek MS; ISABELA 1 and 2 Investigators.
Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials.
JAMA. 2023 May 9;329(18):1567-1578. doi: 10.1001/jama.2023.5355. PMID: 37159034; PMCID: PMC10170340.
Yi D, Reilly CC, Wei G, Higginson IJ;
OPTBreathe collaborators. Optimising breathlessness triggered services for older people with advanced diseases: a multicentre economic study (OPTBreathe).
Thorax. 2023 May;78(5):489-495. doi: 10.1136/thoraxjnl-2021-218251. Epub 2022 Aug 15. PMID: 35970540; PMCID: PMC10176396.
Ferreira DH, Kochovska S, Brunelli VN, Currow DC.
Understanding persistent breathlessness: impact on patients and optimal approaches to symptomatic reduction - an overview.
Expert Rev Respir Med. 2023 May;17(5):365-379. doi: 10.1080/17476348.2023.2208348. Epub 2023 May 4. PMID: 37102251.
Reilly CC, Maddocks M, Chalder T, Bristowe K, Higginson IJ.
A randomised, controlled, feasibility trial of an online, self-guided breathlessness supportive intervention (SELF-BREATHE) for individuals with chronic breathlessness due to advanced disease.
ERJ Open Res. 2023 Apr 11;9(2):00508-2022. doi: 10.1183/23120541.00508-2022. PMID: 37057089; PMCID: PMC10086687.
Simon ST, Mori M, Ekström M, Pralong A, Yamaguchi T, Hui D.
Should Benzodiazepines be Used for Reducing Dyspnea in Patients with Advanced Illnesses?
J Pain Symptom Manage. 2023 Mar;65(3):e219-e223. doi: 10.1016/j.jpainsymman.2022.11.018. Epub 2022 Nov 29. PMID: 36455801.
Kahnert K, Gerckens M.
Spirometrie zeigt COPD früher an als gedacht.
MMW Fortschr Med. 2023 Mar;165(6):29. German. doi: 10.1007/s15006-023-2500-4. PMID: 36961700.
Kochovska S, Ekström M, Hansen-Flaschen J, Ferreira D, Similowski T, Johnson MJ, Currow DC.
Hiding in plain sight: the evolving definition of chronic breathlessness and new ICD-11 wording.
Eur Respir J. 2023 Mar 30;61(3):2300252. doi: 10.1183/13993003.00252-2023. PMID: 36997231.
Rajan SK, Cottin V, Dhar R, Danoff S, Flaherty KR, Brown KK, Mohan A, Renzoni E, Mohan M, Udwadia Z, Shenoy P, Currow D, Devraj A, Jankharia B, Kulshrestha R, Jones S, Ravaglia C, Quadrelli S, Iyer R, Dhooria S, Kolb M, Wells AU.
Progressive pulmonary fibrosis: an expert group consensus statement.
Eur Respir J. 2023 Mar 30;61(3):2103187. doi: 10.1183/13993003.03187-2021. PMID: 36517177; PMCID: PMC10060665.
Murray MA, Mulryan K, Ní Chléirigh M, Redmond KC, Kelly E.
Caring for patients with advanced COPD: beyond the inhalers….
Breathe (Sheff). 2023 Mar;19(1):220229. doi: 10.1183/20734735.0229-2022. Epub 2023 May 23. PMID: 37378065; PMCID: PMC10292785.
Mooren K, Atsma EM, Duinker E, Kerstjens HAM, Currow D, Engels Y.
"This is What Lies Ahead". Perspectives of Oxygen-Naïve COPD Patients on Long-Term Oxygen Use. A Qualitative Study.
Int J Chron Obstruct Pulmon Dis. 2023 Mar 1;18:181-188. doi: 10.2147/COPD.S391095. PMID: 36883015; PMCID: PMC9985978.
Patel S, Jones SE, Walsh JA, Barker RE, Polgar O, Maddocks M, Hopkinson NS, Nolan CM, Man WD.
The Six-minute Step Test as an Exercise Outcome in Chronic Obstructive Pulmonary Disease.
Ann Am Thorac Soc. 2023 Mar;20(3):476-479. doi: 10.1513/AnnalsATS.202206-516RL. PMID: 36240127; PMCID: PMC9993159.
Trudzinski FC, Kellerer C, Jörres RA, Alter P, Lutter JI, Trinkmann F, Herth FJF, Frankenberger M, Watz H, Vogelmeier CF, Kauczor HU, Welte T, Behr J, Bals R, Kahnert K.
Gender-specific differences in COPD symptoms and their impact for the diagnosis of cardiac comorbidities.
Clin Res Cardiol. 2023 Feb;112(2):177-186. doi: 10.1007/s00392-021-01915-x. Epub 2021 Jul 31. PMID: 34331588; PMCID: PMC9898364.
Seidl H, Schunk M, Le L, Syunyaeva Z, Streitwieser S, Berger U, Mansmann U, Szentes BL, Bausewein C, Schwarzkopf L.
Cost-Effectiveness of a Specialized Breathlessness Service Versus Usual Care for Patients With Advanced Diseases.
Value Health. 2023 Jan;26(1):81-90. doi: 10.1016/j.jval.2022.08.002. Epub 2022 Sep 29. PMID: 36182632.
Brighton LJ, Nolan CM, Barker RE, Patel S, Walsh JA, Polgar O, Kon SSC, Gao W, Evans CJ, Maddocks M, Man WDC.
Frailty and Mortality Risk in COPD: A Cohort Study Comparing the Fried Frailty Phenotype and Short Physical Performance Battery.
Int J Chron Obstruct Pulmon Dis. 2023 Jan 20;18:57-67. doi: 10.2147/COPD.S375142. PMID: 36711228; PMCID: PMC9880562.
Nakayama M, Marchi H, Dmitrieva AM, Chakraborty A, Merl-Pham J, Hennen E, Le Gleut R, Ruppert C, Guenther A, Kahnert K, Behr J, Hilgendorff A, Hauck SM, Adler H, Staab-Weijnitz CA.
Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection.
Front Microbiol. 2023 Jan 11;13:957830. doi: 10.3389/fmicb.2022.957830. PMID: 36713229; PMCID: PMC9875134.
Buttery SC, Williams PJ, Brighton LJ, Batista C, Dewar A, Hogg L, Ingram K, Korff G, Koulopoulou M, Lammin H, Maddocks M, McDonnell L, Mehta B, Meyrick V, Pritchard L, Smith O, Trivedi P, Lawson RA, Hopkinson NS.
Development and implementation of the lung volume reduction pulmonary rehabilitation tool to identify eligibility for lung volume reduction in people with chronic obstructive pulmonary disease during pulmonary rehabilitation.
Chron Respir Dis. 2023 Jan-Dec;20:14799731231198863. doi: 10.1177/14799731231198863. PMID: 37658799; PMCID: PMC10475255.
Kotlinska-Lemieszek A, Fopka-Kowalczyk M, Krajnik M.
Spirituality in people with advanced chronic obstructive pulmonary disease - challenge for more effective interventions, support, and healthcare education: Mini-review.
Front Med (Lausanne). 2022 Dec 6;9:954519. doi: 10.3389/fmed.2022.954519. PMID: 36561722; PMCID: PMC9763313.
Brighton LJ, Chilcot J, Maddocks M.
Social dimensions of chronic respiratory disease: stigma, isolation, and loneliness.
Curr Opin Support Palliat Care. 2022 Dec 1;16(4):195-202. doi: 10.1097/SPC.0000000000000616. Epub 2022 Sep 13. PMID: 36102929.
Vaccaro V, Cruz J.
Overview of the new ERS Clinical Practice Guidelines Methodology Network.
Breathe (Sheff). 2022 Dec;18(4):220213. doi: 10.1183/20734735.0213-2022. Epub 2022 Dec 13. PMID: 36865935; PMCID: PMC9973459.
Barbetta C, Allgar V, Maddocks M, Ribeiro C, Wilcock A, Currow DC, Phillips J, Johnson MJ.
Australia-modified Karnofsky Performance Scale and physical activity in COPD and lung cancer: an exploratory pooled data analysis.
BMJ Support Palliat Care. 2022 Dec;12(e6):e759-e762. doi: 10.1136/bmjspcare-2019-001869. Epub 2019 Jul 11. PMID: 31296518.
Piotrowski WJ, Martusewicz-Boros MM, Bialas AJ, Barczyk A, Batko B, Blasinska K, Boros PW, Górska K, Grzanka P, Jassem E, Jastrzebski D, Kaczynska J, Kowal-Bielecka O, Kucharz E, Kus J, Kuznar-Kaminska B, Kwiatkowska B, Langfort R, Lewandowska K, Mackiewicz B, Majewski S, Makowska J, Milkowska-Dymanowska J, Puscinska E, Sieminska A, Sobiecka M, Soroka-Dada RA, Szolkowska M, Wiatr E, Ziora D, Sliwinski P.
Guidelines of the Polish Respiratory Society on the Diagnosis and Treatment of Progressive Fibrosing Interstitial Lung Diseases Other than Idiopathic Pulmonary Fibrosis.
Adv Respir Med. 2022 Oct 4;90(5):425-450. doi: 10.3390/arm90050052. PMID: 36285980; PMCID: PMC9717335.
Seidl H, Schunk M, Le L, Syunyaeva Z, Streitwieser S, Berger U, Mansmann U, Szentes BL, Bausewein C, Schwarzkopf L.
Cost-Effectiveness of a Specialized Breathlessness Service Versus Usual Care for Patients With Advanced Diseases.
Value Health. 2023 Jan;26(1):81-90. doi: 10.1016/j.jval.2022.08.002. Epub 2022 Sep 29. PMID: 36182632.
Kowalczys A, Bohdan M, Wilkowska A, Pawlowska I, Pawlowski L, Janowiak P, Jassem E, Lelonek M, Gruchala M, Sobanski P.
Comprehensive care for people living with heart failure and chronic obstructive pulmonary disease-Integration of palliative care with disease-specific care: From guidelines to practice.
Front Cardiovasc Med. 2022 Sep 27;9:895495. doi: 10.3389/fcvm.2022.895495. PMID: 36237915; PMCID: PMC9551106.
Reilly CC, Bristowe K, Roach A, Chalder T, Maddocks M, Higginson IJ.
"The whole of humanity has lungs, doesn't it? We are not all the same sort of people": patient preferences and choices for an online, self-guided chronic breathlessness supportive intervention: SELF-BREATHE.
ERJ Open Res. 2022 Jul 11;8(3):00093-2022. doi: 10.1183/23120541.00093-2022. PMID: 35821758; PMCID: PMC9271754.
Reitzel T, Bergmann A, Schloesser K, Pauli B, Eisenmann Y, Randerath W, Tuchscherer A, Frank K, Simon ST, Pralong A.
The experience of episodic breathlessness from the perspective of informal caregivers: a qualitative interview study.
Ann Palliat Med. 2022 Jul;11(7):2225-2234. doi: 10.21037/apm-21-3361. Epub 2022 Mar 16. PMID: 35306824.
Schloesser K, Bergmann A, Eisenmann Y, Pauli B, Hellmich M, Oberste M, Hamacher S, Tuchscherer A, Frank KF, Randerath W, Herkenrath S, Simon ST.
Only I Know Now, of Course, How to Deal With it, or Better to Deal With it: A Mixed Methods Phase II Study of a Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness.
J Pain Symptom Manage. 2022 May;63(5):758-768. doi: 10.1016/j.jpainsymman.2021.11.003. Epub 2021 Nov 15. PMID: 34793948.
Fettes L, Neo J, Ashford S, Higginson IJ, Maddocks M.
Trajectories of disability in activities of daily living in advanced cancer or respiratory disease: a systematic review.
Disabil Rehabil. 2022 May;44(10):1790-1801. doi: 10.1080/09638288.2020.1820587. Epub 2020 Sep 22. PMID: 32961067.
Luckett T, Roberts M, Smith T, Garcia M, Dunn S, Swan F, Ferguson C, Kochovska S, Phillips JL, Pearson M, Currow DC, Johnson MJ.
Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians.
BMC Pulm Med. 2022 Apr 6;22(1):129. doi: 10.1186/s12890-022-01925-z. PMID: 35387636; PMCID: PMC8985391.
Gabrielli M, Pignataro G, Candelli M, Sacco Fernandez M, Bizzarri M, Esperide A, Franceschi F; GEMELLI AGAINST COVID 2019.
Asthma in patients admitted to emergency department for COVID-19: prevalence and risk of hospitalization.
Intern Emerg Med. 2022 Apr;17(3):917-920. doi: 10.1007/s11739-021-02868-9. Epub 2021 Oct 17. PMID: 34657266; PMCID: PMC8520500.
Reitzel T, Bergmann A, Schloesser K, Pauli B, Eisenmann Y, Randerath W, Tuchscherer A, Frank K, Simon ST, Pralong A.
The experience of episodic breathlessness from the perspective of informal caregivers: a qualitative interview study.
Ann Palliat Med. 2022 Mar 16:apm-21-3361. doi: 10.21037/apm-21-3361. Epub ahead of print. PMID: 35306824.
Reilly CC, Bristowe K, Roach A, Maddocks M, Higginson IJ.
"You can do it yourself and you can do it at your convenience": internet accessibility and willingness of people with chronic breathlessness to use an internet-based breathlessness self-management intervention during the COVID-19 pandemic.
ERJ Open Res. 2022 Feb 21;8(1):00557-2021. doi: 10.1183/23120541.00557-2021. PMID: 35198627; PMCID: PMC8859502.
Krajnik M, Hepgul N, Wilcock A, Jassem E, Bandurski T, Tanzi S, Simon ST, Higginson IJ, Jolley CJ; BETTER-B research consortium.
Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians.
BMC Pulm Med. 2022 Jan 19;22(1):41. doi: 10.1186/s12890-022-01835-0. PMID: 35045847; PMCID: PMC8768441.
Cristea L, Olsson M, Currow D, Johnson M, Sandberg J, Ekström M.
Breathlessness dimensions association with physical and mental quality of life: the population based VASCOL study of elderly men.
BMJ Open Respir Res. 2021 Nov;8(1):e000990. doi: 10.1136/bmjresp-2021-000990. PMID: 34740943; PMCID: PMC8573661.
Schunk M, Berger U, Le L, Rehfuess E, Schwarzkopf L, Streitwieser S, Müller T, Hofmann M, Holle R, Huber RM, Mansmann U, Bausewein C.
BreathEase: rationale, design and recruitment of a randomised trial and embedded mixed-methods study of a multiprofessional breathlessness service in early palliative care.
ERJ Open Res. 2021 Oct 18;7(4):00228-2020. doi: 10.1183/23120541.00228-2020. PMID: 34671668; PMCID: PMC8521025.
Adeloye D, Agarwal D, Barnes PJ, Bonay M, van Boven JF, Bryant J, Caramori G, Dockrell D, D'Urzo A, Ekström M, Erhabor G, Esteban C, Greene CM, Hurst J, Juvekar S, Khoo EM, Ko FW, Lipworth B, López-Campos JL, Maddocks M, Mannino DM, Martinez FJ, Martinez-Garcia MA, McNamara RJ, Miravitlles M, Pinnock H, Pooler A, Quint JK, Schwarz P, Slavich GM, Song P, Tai A, Watz H, Wedzicha JA, Williams MC, Campbell H, Sheikh A, Rudan I.
Research priorities to address the global burden of chronic obstructive pulmonary disease (COPD) in the next decade.
J Glob Health. 2021 Oct 9;11:15003. doi: 10.7189/jogh.11.15003. PMID: 34737870; PMCID: PMC8542376.
Nolan CM, Walsh JA, Patel S, Barker RE, Polgar O, Maddocks M, Gao W, Wilson R, Fiorentino F, Man W.
Minimal versus specialist equipment in the delivery of pulmonary rehabilitation: protocol for a non-inferiority randomised controlled trial.
BMJ Open. 2021 Oct 18;11(10):e047524. doi: 10.1136/bmjopen-2020-047524. PMID: 34663653; PMCID: PMC8524266.
Currow DC, Chang S, Ekström M, Hutchinson A, Luckett T, Kochovska S, Hay P, Touyz S, Dal Grande E, Johnson MJ.
Health service utilisation associated with chronic breathlessness: random population sample.
ERJ Open Res. 2021 Oct 11;7(4):00415-2021. doi: 10.1183/23120541.00415-2021. PMID: 34651042; PMCID: PMC8503326.
Gabrielli M, Pignataro G, Candelli M, Sacco Fernandez M, Bizzarri M, Esperide A, Franceschi F; GEMELLI AGAINST COVID 2019.
Asthma in patients admitted to emergency department for COVID-19: prevalence and risk of hospitalization.
Intern Emerg Med. 2021 Oct 17. doi: 10.1007/s11739-021-02868-9. Epub ahead of print. PMID: 34657266.
Reedy F, Pearson M, Greenley S, Clark J, Currow DC, Bajwah S, Fallon M, Johnson MJ.
Professionals', patients' and families' views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process.
Palliat Med. 2021 Sep;35(8):1421-1433. doi: 10.1177/02692163211032114. Epub 2021 Jul 24. PMID: 34304624.
Wasilewska E, Sobierajska-Rek A, Malgorzewicz S, Solinski M, Szalewska D, Jassem E.
Is It Possible to Have Home E-Monitoring of Pulmonary Function in Our Patients with Duchenne Muscular Dystrophy in the COVID-19 Pandemic?-A One Center Pilot Study.
Int J Environ Res Public Health. 2021 Aug 26;18(17):8967. doi: 10.3390/ijerph18178967. PMID: 34501557; PMCID: PMC8430665.
Currow DC, Chang S, Ferreira D, Eckert DJ, Gonzalez-Chica D, Stocks N, Ekström MP.
Chronic breathlessness and sleep problems: a population-based survey.
BMJ Open. 2021 Aug 12;11(8):e046425. doi: 10.1136/bmjopen-2020-046425. PMID: 34385238; PMCID: PMC8362739.
Fettes L, Bayly J, de Bruin LM, Patel M, Ashford S, Higginson IJ, Maddocks M.
Relationships between prolonged physical and social isolation during the COVID-19 pandemic, reduced physical activity and disability in activities of daily living among people with advanced respiratory disease.
Chron Respir Dis. 2021 Jan-Dec;18:14799731211035822. doi: 10.1177/14799731211035822. PMID: 34382888; PMCID: PMC8370888.
Aronson KI, Danoff SK, Russell AM, Ryerson CJ, Suzuki A, Wijsenbeek MS, Bajwah S, Bianchi P, Corte TJ, Lee JS, Lindell KO, Maher TM, Martinez FJ, Meek PM, Raghu G, Rouland G, Rudell R, Safford MM, Sheth JS, Swigris JJ.
Patient-centered Outcomes Research in Interstitial Lung Disease: An Official American Thoracic Society Research Statement.
Am J Respir Crit Care Med. 2021 Jul 15;204(2):e3-e23. doi: 10.1164/rccm.202105-1193ST. Erratum in: Am J Respir Crit Care Med. 2021 Sep 1;204(5):616. PMID: 34283696.
Connellan D, Diffley K, McCabe J, Cotter A, McGinty T, Sheehan G, Ryan K, Cullen W, Lambert JS, Callaly EL, Kyne L.
Documentation of Do-Not-Attempt-Cardiopulmonary-Resuscitation orders amid the COVID-19 pandemic.
Age Ageing. 2021 Jun 28;50(4):1048-1051. doi: 10.1093/ageing/afab075. PMID: 33909020; PMCID: PMC8135469.
Schloesser K, Eisenmann Y, Bergmann A, Simon ST.
Development of a Brief Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness-A Delphi Survey With International Experts.
J Pain Symptom Manage. 2021 May;61(5):963-973.e1. doi: 10.1016/j.jpainsymman.2020.09.034. Epub 2020 Sep 28. PMID: 33002596.
Disler R, Pascoe A, Luckett T, Donesky D, Irving L, Currow DC, Smallwood N.
Barriers to Palliative Care Referral and Advance Care Planning (ACP) for Patients With COPD: A Cross-Sectional Survey of Palliative Care Nurses.
Am J Hosp Palliat Care. 2021 May 20:10499091211018192. doi: 10.1177/10499091211018192. Epub ahead of print. PMID: 34013782.
Poulos LM, Ampon RD, Currow DC, Marks GB, Toelle BG, Reddel HK.
Prevalence and burden of breathlessness in Australian adults: The National Breathlessness Survey-a cross-sectional web-based population survey.
Respirology. 2021 May 10. doi: 10.1111/resp.14070. Epub ahead of print. PMID: 33971059.
Schloesser K, Eisenmann Y, Bergmann A, Simon ST.
Development of a Brief Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness-A Delphi Survey With International Experts.
J Pain Symptom Manage. 2021 May;61(5):963-973.e1. doi: 10.1016/j.jpainsymman.2020.09.034. Epub 2020 Sep 28. PMID: 33002596.
Barker RE, Brighton LJ, Maddocks M, Nolan CM, Patel S, Walsh JA, Polgar O, Wenneberg J, Kon SSC, Wedzicha JA, Man WDC, Farquhar M.
Integrating Home-Based Exercise Training with a Hospital at Home Service for Patients Hospitalised with Acute Exacerbations of COPD: Developing the Model Using Accelerated Experience-Based Co-Design.
Int J Chron Obstruct Pulmon Dis. 2021 Apr 19;16:1035-1049. doi: 10.2147/COPD.S293048. PMID: 33907391; PMCID: PMC8064617.
Slevin P, Kessie T, Cullen J, Butler MW, Donnelly SC, Caulfield B.
A qualitative study of clinician perceptions regarding the potential role for digital health interventions for the management of COPD.
Health Informatics J. 2021 Jan-Mar;27(1):1460458221994888. doi: 10.1177/1460458221994888. PMID: 33653189.
Northgraves M, Cohen J, Allgar V, Currow D, Hart S, Hird K, Hodge A, Johnson M, Mason S, Swan F, Hutchinson A.
A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE).
ERJ Open Res. 2021 Mar 29;7(1):00955-2020. doi: 10.1183/23120541.00955-2020. PMID: 33816602; PMCID: PMC8005684.
Kochovska S, Ferreira DH, Garcia MV, Phillips JL, Currow DC.
Perspectives on palliative oxygen for breathlessness: Systematic review and meta-synthesis.
Eur Respir J. 2021 Mar 2:2004613. doi: 10.1183/13993003.04613-2020. Epub ahead of print. PMID: 33653807.
Brighton LJ, Evans CJ, Farquhar M, Bristowe K, Kata A, Higman J, Ogden M, Nolan C, Yi D, Gao W, Koulopoulou M, Hasan S, Steves CJ, Man WD, Maddocks M.
Integrating Comprehensive Geriatric Assessment for people with COPD and frailty starting pulmonary rehabilitation: the Breathe Plus feasibility trial protocol.
ERJ Open Res. 2021 Mar 29;7(1):00717-2020. doi: 10.1183/23120541.00717-2020. PMID: 33816606; PMCID: PMC8005693.
Barker RE, Kon SS, Clarke SF, Wenneberg J, Nolan CM, Patel S, Walsh JA, Polgar O, Maddocks M, Farquhar M, Hopkinson NS, Bell D, Wedzicha JA, Man WD.
COPD discharge bundle and pulmonary rehabilitation referral and uptake following hospitalisation for acute exacerbation of COPD.
Thorax. 2021 Mar 2:thoraxjnl-2020-215464. doi: 10.1136/thoraxjnl-2020-215464. Epub ahead of print. PMID: 33653933.
Patel S, Palmer MD, Nolan CM, Barker RE, Walsh JA, Wynne SC, Jones SE, Shannon H, Hopkinson NS, Kon SSC, Gao W, Maddocks M, Man WD.
Supervised pulmonary rehabilitation using minimal or specialist exercise equipment in COPD: a propensity-matched analysis.
Thorax. 2021 Mar;76(3):264-271. doi: 10.1136/thoraxjnl-2020-215281. Epub 2020 Nov 1. PMID: 33132208; PMCID: PMC7892370.
Ekström M, Bornefalk H, Sköld CM, Janson C, Blomberg A, Sandberg J, Bornefalk-Hermansson A, Currow DC, Johnson MJ, Sundh J.
Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study.
Eur Respir J. 2021 Mar 25;57(3):2002823. doi: 10.1183/13993003.02823-2020. PMID: 33334935.
Hui D, Bohlke K, Bao T, Campbell TC, Coyne PJ, Currow DC, Gupta A, Leiser AL, Mori M, Nava S, Reinke LF, Roeland EJ, Seigel C, Walsh D, Campbell ML.
Management of Dyspnea in Advanced Cancer: ASCO Guideline.
J Clin Oncol. 2021 Apr 20;39(12):1389-1411. doi: 10.1200/JCO.20.03465. Epub 2021 Feb 22. PMID: 33617290.
Schunk M, Le L, Syunyaeva Z, Haberland B, Tänzler S, Mansmann U, Schwarzkopf L, Seidl H, Streitwieser S, Hofmann M, Müller T, Weiß T, Morawietz P, Rehfuess EA, Huber RM, Berger U, Bausewein C.
Effectiveness of a specialised breathlessness service for patients with advanced disease in Germany: a pragmatic fast track randomised controlled trial (BreathEase).
Eur Respir J. 2021 Feb 11:2002139. doi: 10.1183/13993003.02139-2020. Epub ahead of print. PMID: 33509957.
Barnes-Harris M, Allingham S, Morgan D, Ferreira D, Johnson MJ, Eagar K, Currow D.
Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: lung cancers and non-malignant end-stage respiratory diseases.
Thorax. 2021 Feb 16:thoraxjnl-2020-216039. doi: 10.1136/thoraxjnl-2020-216039. Epub ahead of print. PMID: 33593929.
Genberg J, Davies JM, Ahmadi Z, Currow D, Johnson MJ, Tanash H, Bajwah S, Ekström M.
Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study.
ERJ Open Res. 2021 Feb 1;7(1):00716-2020. doi: 10.1183/23120541.00716-2020. PMID: 33569492; PMCID: PMC7861020.
Bajwah S, Colquitt J, Loveman E, Bausewein C, Almond H, Oluyase A, Dzingina M, Maddocks M, Higginson IJ, Wells A.
Pharmacological and nonpharmacological interventions to improve symptom control, functional exercise capacity and quality of life in interstitial lung disease: an evidence synthesis.
ERJ Open Res. 2021 Jan 25;7(1):00107-2020. doi: 10.1183/23120541.00107-2020. PMID: 33532482; PMCID: PMC7836673.
Hui D, Maddocks M, Johnson MJ, Ekström M, Simon ST, Ogliari AC, Booth S, Ripamonti C;ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org.
Management of breathlessness in patients with cancer: ESMO Clinical Practice Guidelines†.
ESMO Open. 2020 Dec;5(6):e001038. doi: 10.1136/esmoopen-2020-001038. PMID: 33303485; PMCID: PMC7733213.
Luckett T, San Martin A, Currow DC, Johnson MJ, Barnes-Harris MM, Phillips JL.
A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease.
Palliat Med. 2020 Dec;34(10):1291-1304. doi: 10.1177/0269216320940153. Epub 2020 Jul 28. PMID: 32720568.
Akbarshahi H, Ahmadi Z, Currow DC, Sandberg J, Vandersman Z, Shanon-Honson A, Ekström M.
No gender-related bias in COPD diagnosis and treatment in Sweden: a randomised, controlled, case-based trial.
ERJ Open Res. 2020 Nov 10;6(4):00342-2020. doi: 10.1183/23120541.00342-2020. PMID: 33263044; PMCID: PMC7682677.
Currow DC, Chang S, Grande ED, Ferreira DH, Kochovska S, Kinchin I, Johnson MJ, Ekstrom M.
Quality of Life Changes With Duration of Chronic Breathlessness: A Random Sample of Community-Dwelling People.
J Pain Symptom Manage. 2020 Oct;60(4):818-827.e4. doi: 10.1016/j.jpainsymman.2020.05.015. Epub 2020 May 20. PMID: 32442480.
Currow DC, Kochovska S, Ferreira D, Johnson M.
Morphine for the symptomatic reduction of chronic breathlessness: the case for controlled release.
Curr Opin Support Palliat Care. 2020 Sep;14(3):177-181. doi: 10.1097/SPC.0000000000000520. PMID: 32740277.
Fettes L, Neo J, Ashford S, Higginson IJ, Maddocks M.
Trajectories of disability in activities of daily living in advanced cancer or respiratory disease: a systematic review.
Disabil Rehabil. 2020 Sep 22:1-12. doi: 10.1080/09638288.2020.1820587. Epub ahead of print. PMID: 32961067.
Johnson MJ, Currow DC.
Opioids for breathlessness: a narrative review.
BMJ Support Palliat Care. 2020 Sep;10(3):287-295. doi: 10.1136/bmjspcare-2020-002314. Epub 2020 Jul 3. PMID: 32620683.
Currow DC, Johnson MJ, Pollack A, Ferreira DH, Kochovska S, Ekström M, Harrison C.
Breathlessness and opioid prescribing in COPD in general practice: a cross-sectional, observational study.
ERJ Open Res. 2020 Jul 6;6(2):00299-2019. doi: 10.1183/23120541.00299-2019. PMID: 32775398; PMCID: PMC7402382.
Tanghe M, Van Den Noortgate N, Deliens L, Smets T, Onwuteaka-Philipsen B, Szczerbinska K, Finne-Soveri H, Payne S, Gambassi G, Van den Block L, Piers R.
Opioid underuse in terminal care of long-term care facility residents with pain and/or dyspnoea: A cross-sectional PACE-survey in six European countries.
Palliat Med. 2020 Jun;34(6):784-794. doi: 10.1177/0269216320910332. Epub 2020 Apr 14. PMID: 32286149.
Ferreira DH, Kochovska S, Honson A, Phillips JL, Currow DC.
Two faces of the same coin: a qualitative study of patients' and carers' coexistence with chronic breathlessness associated with chronic obstructive pulmonary disease (COPD).
BMC Palliat Care. 2020 May 6;19(1):64. doi: 10.1186/s12904-020-00572-7. PMID: 32375747; PMCID: PMC7203967.
Henson LA, Maddocks M, Evans C, Davidson M, Hicks S, Higginson IJ.
Palliative Care and the Management of Common Distressing Symptoms in Advanced Cancer: Pain, Breathlessness, Nausea and Vomiting, and Fatigue.
J Clin Oncol. 2020 Mar 20;38(9):905-914. doi: 10.1200/JCO.19.00470. Epub 2020 Feb 5. PMID: 32023162; PMCID: PMC7082153.
Piotrowski WJ, Bestry I, Bialas AJ, Boros PW, Grzanka P, Jassem E, Jastrzebski D, Klimczak D, Langfort R, Lewandowska K, Majewski S, Martusewicz-Boros MM, Onisch K, Puscinska E, Sieminska A, Sobiecka M, Szolkowska M, Wiatr E, Wilczynski G, Ziora D, Kus J.
Guidelines of the Polish Respiratory Society for diagnosis and treatment of idiopathic pulmonary fibrosis.
Adv Respir Med. 2020;88(1):41-93. doi: 10.5603/ARM.2020.0081. PMID: 32153010.
Kreuter M, Wuyts WA, Wijsenbeek M, Bajwah S, Maher TM, Stowasser S, Male N, Stansen W, Schoof N, Orsatti L, Swigris J.
Health-related quality of life and symptoms in patients with IPF treated with nintedanib: analyses of patient-reported outcomes from the INPULSIS® trials.
Respir Res. 2020 Jan 30;21(1):36. doi: 10.1186/s12931-020-1298-1. PMID: 32000772; PMCID: PMC6990488.
Currow DC, Hunt T, Louw S, Eckert D, Allcroft P, To THM, Greene A, Krajnik M, Mahler D, Ekström M.
Isolating peripheral effects of endogenous opioids in modulating exertional breathlessness in people with moderate or severe COPD: a randomised controlled trial.
ERJ Open Res. 2019 Dec 23;5(4):00153-2019. doi: 10.1183/23120541.00153-2019. PMID: 31886161; PMCID: PMC6926367.
Lovell N, Etkind SN, Bajwah S, Maddocks M, Higginson IJ.
To What Extent Do the NRS and CRQ Capture Change in Patients' Experience of Breathlessness in Advanced Disease? Findings From a Mixed-Methods Double-Blind Randomized Feasibility Trial.
J Pain Symptom Manage. 2019 Sep;58(3):369-381.e7. doi: 10.1016/j.jpainsymman.2019.06.004. Epub 2019 Jun 13. PMID: 31201877.
Slevin P, Kessie T, Cullen J, Butler MW, Donnelly SC, Caulfield B.
A qualitative study of chronic obstructive pulmonary disease patient perceptions of the barriers and facilitators to adopting digital health technology.
Digit Health. 2019 Aug 25;5:2055207619871729. doi: 10.1177/2055207619871729. PMID: 31489206; PMCID: PMC6710666.
Barbetta C, Allgar V, Maddocks M, Ribeiro C, Wilcock A, Currow DC, Phillips J, Johnson MJ.
Australia-modified Karnofsky Performance Scale and physical activity in COPD and lung cancer: an exploratory pooled data analysis.
BMJ Support Palliat Care. 2019 Jul 11:bmjspcare-2019-001869. doi: 10.1136/bmjspcare-2019-001869. Epub ahead of print. PMID: 31296518.
Swan F, Newey A, Bland M, Allgar V, Booth S, Bausewein C, Yorke J, Johnson M.
Airflow relieves chronic breathlessness in people with advanced disease: An exploratory systematic review and meta-analyses.
Palliat Med. 2019 Jun;33(6):618-633. doi: 10.1177/0269216319835393. Epub 2019 Mar 8. PMID: 30848701.
Schunk M, Schulze F, Bausewein C.
What Constitutes Good Health Care for Patients with Breathlessness? Perspectives of Patients, Caregivers, and Health Care Professionals.
J Palliat Med. 2019 Jun;22(6):656-662. doi: 10.1089/jpm.2018.0319. Epub 2018 Dec 27. PMID: 30589622.
Brozek B, Fopka-Kowalczyk M, Labus-Centek M, Damps-Konstanska I, Ratajska A, Jassem E, Larkin P, Krajnik M.
Dignity Therapy as an aid to coping for COPD patients at their end-of-life stage.
Adv Respir Med. 2019;87(3):135-145. doi: 10.5603/ARM.a2019.0021. Epub 2019 May 6. PMID: 31058308.
Brozek B, Damps-Konstanska I, Pierzchala W, Barczyk A, Currow DC, Jassem E, Krajnik M.
End-of-life care for patients with advanced lung cancer and chronic obstructive pulmonary disease: survey among Polish pulmonologists.
Pol Arch Intern Med. 2019 Apr 30;129(4):242-252. doi: 10.20452/pamw.4478. Epub 2019 Mar 5. PMID: 30833536.
Bajwah S, Davies JM, Tanash H, Currow DC, Oluyase AO, Ekström M.
Safety of benzodiazepines and opioids in interstitial lung disease: a national prospective study.
Eur Respir J. 2018 Dec 6;52(6):1801278. doi: 10.1183/13993003.01278-2018. PMID: 30309973.